fig3

Figure 3. Potential direct and indirect effects of GLP-1Ra and SGLT2i on HPG axis function, CV system function and insulin resistance in diabetic hypogonadal men. FSH: follicle-stimulating hormone; LH: luteinizing hormone; GnRH, Gonadotropin-releasing hormone; GLP-1Ra: glucagon-like peptide-1 receptor agonist; KISS-1: kisspeptin-1; SGLT2i: sodium-glucose cotransporter protein-2 inhibitor; HPG: hypothalamus-pituitary-gonadal.